Decreased levels of TDP-43 gene may be contributing to neurodegenerative diseases like Alzheimer’s and ALS
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Four Clinical Variables Predict RA Development in Arthralgia
TOPLINE:In individuals with seropositive arthralgia, the risk of developing rheumatoid arthritis (RA) rose in the presence of high titers of anti–citrullinated peptide antibodies (ACPAs) and immunoglobulin M-rheumatoid factor (IgM-RF), along with baseline factors, such as first-degree relative status, intermittent symptoms, and morning stiffness. METHODOLOGY:Researchers conducted a 5-year follow-up study to identify the risk factors for […] More
Higher Persistent PSA Level: A Bad Omen?
TOPLINE:Higher persistent PSA levels post-surgery were linked to increased mortality risk, with 8-year prostate cancer–specific mortality reaching 13.86% for a prostate-specific antigen (PSA) ≥ 1 ng/mL. METHODOLOGY:The conventional 1.5-month to 2.0-month time interval following radical prostatectomy (RP) for assessing persistent PSA remained questionable for accuracy.Analysis included 43,298 patients with clinical stage T1N0M0 to T3N0M0 prostate […] More